According to American Cancer Society and Cancer Research UK, the estimated breast cancer in the United States and UK are:
| US (Year 2016) | UK (Year 2014) | |
| New cases of invasive breast cancer | About 246,660 new cases | About 55,222 new cases |
| New cases of Carcinoma In Situ (earliest form of breast cancer) | About 61,000 new cases | - |
| Deaths from breast cancer | About 40,450 cases | About 11,433 cases |
While breast cancer affects 1 in 8 women during their lives, there have been many life-saving treatment advances against breast cancer, thanks to the significant cancer research effort by medical professionals who bring new hope and help millions of women survived breast cancer today.
We look into the medical study, clinical results, and AHCC supplement user reviews on the use of AHCC as complementary and alternative medicine (CAM) in breast cancer treatment:
AHCC Breast Cancer Research #1: Clinical Study, Medical Results.
Source:
International Society of Personalized Medicine
Topic:
Review of Cancer Therapy with AHCC and GCP: The Long-Term Follow-Up over 12 Years for Stage IV (M1) Cancer of the Lung and the Breast
Abstract:
AHCC and GCP have been used for 34 stage IV breast cancer patients who were enrolled under individual Evidence Based Medicine (EBM). Long-term follow-up for 12 years from 1996 to 2009 has been carried out.
Results / Conclusion:
- 22 of 34 patients passed away and 12 patients are alive.
- Cumulative survival rate of 1-year, 2-year, 3-year, 4-year and 5-year are 100.0%, 84.4%, 68.3%, 47.9% and 36.8%, respectively. Median survival terms were 47.86 months.
- This study suggests that AHCC and GCP could contribute to the extension of survival terms and improved QOL on breast cancer therapy.
AHCC Breast Cancer Research #2: Dosage, Clinical Study, Results.
Source:
International Journal of Immunotherapy
Topic:
Does AHCC have immunomodulatory and anti-cancer effects in cancer patients?
Abstract:
11 cancer patients with advanced malignancies were treated with AHCC for up to 17 months. Tumor-associated antigens (TAAs) for each type of malignancy was measured prior to AHCC treatment and at 3- to 40-week intervals. Natural killer (NK) cell activity was also monitored.
AHCC Dosage:
3 grams of AHCC per day.
Results:
Supplementation with AHCC showed positive clinical results with:
- A significant decline in TAA occurred in 8 out of the 11 patients with different types of malignancies.
- Breast cancer patients shows 33% (1 out of 3) complete remission rate, and 2 out of 3 partial.
- Significant decline in the level of PSA in 2 out of 3 (66%) prostate cancer patients.
- CA 125 levels in 2 out of 3 (66%) ovarian cancer patients decreased as early as 1 to 2 months and reached normal levels within 1 to 4 months.
- 1 out of 2 (50%) multiple myeloma patients had significant reduction in BJP level.
- In vitro studies showed that AHCC possesses suppressive effects on tumor cell growth.
Conclusion:
The high augmentory effect of AHCC and the absence of notable side effects make AHCC a promising immunotherapeutic agent for the treatment of cancer patients.
AHCC Breast Cancer Research #3: Dosage, Clinical Study Results.
Source:
C.R. Drew University of Medicine and Science LA, Egypt Menoufia University etc
Topic:
Enhancement of NK Cell Activity in Cancer Patients by Active Hemicellulose Compound (AHCC)
Abstract:
Patients with rhabdomyosarcoma multiple myeloma and breast cancer were given AHCC, then NK cell cytotoxicity was measured using K562 tumor cells as targets.
Dosage:
3 and 6 grams per day 2 weeks.
Results / Conclusion:
Treatment with AHCC demonstrated significant enhancement in NK anticancer activity for breast cancer (93%) and for multiple myeloma (87%). In addition, 2-3 fold elevation of NK populations was also observed in both patients.
It is concluded that AHCC has the potential to reduce the severity of neutropenia induced by breast cancer chemotherapy and the use of G-CSF during chemotherapy.
AHCC Breast Cancer Research #4: Clinical Study, Medical Results.
Source:
The Journal of Alternative and Complementary Medicine
Topic:
Effect of Active Hexose-Correlated Compound in Women Receiving Adjuvant Chemotherapy for Breast Cancer: A Retrospective Study
Abstract:
41 women who were treated with Anthracyclines and Taxanes (therapies used as first-line chemotherapy treatments breast cancer patients but often associated with significant toxicity and side effects) at Nagumo Clinic in Tokyo from October 2004 to March 2011 were selected for this study, to explore the beneficial effects of AHCC on adverse events in patients receiving adjuvant chemotherapy for breast cancer.
Results / Conclusion:
Comparing the occurrence of adverse events in patients who received AHCC with those who did not receive AHCC (as control group) – the AHCC group had significantly fewer neutrophil-related events, alongside significantly lower use of granulocyte colony-stimulating factor.
It is concluded that AHCC has the potential to reduce the severity of neutropenia induced by breast cancer chemotherapy and the use of G-CSF during chemotherapy.
Best AHCC Supplement Brands and Dosage Review
Just as the clinical studies above that primarily used 3 grams AHCC dose daily –
the International Journal of Clinical Medicine also have similar dosage recommendation that “AHCC up to 3 grams is safe to administer and definitely helps cancer patients in reducing side effects of chemotherapeutic drugs“.
For 3 grams, i.e. 3000 milligrams (mg) daily – based on the best AHCC supplement brands below for examples:
Take 6 capsules (500mg) daily, 3 times a day.
I.e. Total 3 grams a day taken on an empty stomach, 1 hour before food.
| Brand | ImmunoKinoko | Kinoko Platinum | Kinoko Gold AHCC | NOW Foods AHCC |
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AHCC Breast Cancer: User Forum Reviews, Results, Testimonials.
- carolwxyz99, commented at Phoenix Rising:
‘..I have been on AHCC for about 2-3 years now – taking 2000-3000 mg a day. I developed breast cancer on top of my ME/CFS and most integrative cancer docs suggest mushrooms as cancer prevention. I am sensitive to many moulds and fungi and could not tolerate many of the mushroon products but I have been fine with AHCC. The only other mushroom I can tolerate is reishi mushroom when it is boiled with chinese herbs (I can’t tolerate reishi in powder or a tincture). I am very sensitive to products which boost the immune system as they tend to make me flu-like, and usually respond better to immune modulators. I am, however, fine with AHCC – it has not stimulated my immune system in the wrong way.‘
Breast Cancer: AHCC Supplement User Reviews and Results
Recommended Read: AHCC Help Reduce Chemotherapy Side Effects on Cancer Patients
Breast Cancer Treatment and Survival Rate / Life Expectancy by Stage
Breast cancer is curable if detected early. Besides the treatment options, most patients wish to know the breast cancer prognosis “calculator” however the life expectancy depend on many factors, including the age etc as shown in the infographic at the end of this post.
Stage 0 Breast Cancer
There are 2 types of Stage 0 breast cancer, which is a non-invasive precancerous condition at the earliest stage of breast cancer:
- Lobular Carcinoma In Situ (LCIS) where abnormal cells start growing in lobules, the milk-producing glands at the end of breast ducts. Generally not considered as cancer, but women who develop LCIS has 20% to 25% risk of getting invasive cancer over 15 years after initial diagnosis.
- Ductal Carcinoma In Situ (DCIS) where abnormal cells are found in the lining of the breast milk duct. If left untreated, DCIS can become invasive and spread to surrounding breast tissue.
Some doctors may not recommend any treatment for Stage 0 LCIS, and the patient only requires close observations with yearly mammogram and breast exam to watch for breast cancer signs.
Some doctors may prescribe Tamoxifen hormone medication to reduce the risk of breast cancer, while breast-conserving surgery Lumpectomy may be recommended to remove abnormal cells and normal tissues nearby.
DCIS treatment wise, doctors may recommended Lumpectomy only, Lumpectomy combined with radiation therapy, or Mastectomy to surgically remove breast(s).
According to American Cancer Society, 5 year breast cancer survival rate of stage 0 is close to 100%.
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Stage 1 / 2 / 3 / 4 Breast Cancer
Treatment options of breast cancer from stage 1 to stage 3 may include:
- Surgery: Lumpectomy to remove abnormal cells, or Mastectomy to surgically remove breast.
- Radiation Therapy: Uses high doses of radiation to kill cancer cells and shrink tumors.
- Chemotherapy: Drug therapy to kill cancer cells, stopping them from spreading, or slow their growth.
- Hormone Therapy: Drugs like blockers or inhibitors that destroy cancer cells by cutting off their hormone supply.
Stage 4 breast cancer patient may be treated with chemotherapy (and radiation), hormone therapy, and/or targeted therapy with trastuzumab (Herceptin) to stop the protein from making the cancer cells grow. This is for breast cancer patient with too much of a protein known as HER2.
Recommended Read: Practical Items That Improve Breast Cancer Patient’s Quality of Life
Based on statistics published by the American Cancer Society and Cancer Research UK, studies show the 5-years breast cancer survival rate for
- Stage 1 is around 99% to 100%
- Stage 2 is around 87.6% to 93%
- Stage 3 is around 55.1% to 72%
- Stage 4 is around 14.7% to 22%
According to BreastHealth UK, Texas Oncology and other studies, the 10-years survival rates for breast cancer by stage are estimated as below:
- Stage 0 is around 95%
- Stage 1 is around 75% to 85%
- Stage 2 is around 40% to 60%
- Stage 3 is around 36% to 54%
- Stage 4 is around 2% to 13%
Medical authorities like American Cancer Society and Cancer Research UK have not published any official statistics on breast cancer 20 year survival rates, however they did release data on the estimated breast cancer survival rates by age as shown in the video above.
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