When our body immune system does not work the way it should, it is called an immune system disorder, with the causing factors are:
- Born with a weak immune system (source: University of Rochester Medical Center Rochester)
- Get a disease that weakens immune system, eg. HIV infection (source: US AIDS.gov website)
- Cancer treatment such as chemotherapy and radiotherapy (source: Cancer Research UK)
- Human aging that cause immune system becomes less effective (source: MerckManuals)
- Not getting enough sleep (source: WebMD)
- Cigarette smoking
And when our immune system cannot do its job, the adverse health impact may include:
- Allergy and asthma (source: MedlinePlus)
- Autoimmune diseases that cause our immune system to attack own body’s cells by mistake
- Flu, colds, sinus infections.
- Diarrhea, cold sores, chronic infections.
As such, many people look for natural diets and supplements to boost immune support and for overall well being, while some patients seek immune booster injection after chemo and cancer treatment.
Mushrooms that contain long-chain polysaccharides (particularly alpha- and beta-glucan molecules) have proven beneficial effect on human body immune system, with the natural Active Hexose Correlated Compound (AHCC) extract from Japanese Shiitake mushrooms serves as immunomodulatory agent that helps keep our immune system strong and balanced.
According to AHCC research, medical experts and studies testified that AHCC supports immune system by increasing the production of body’s natural killer cells, while it modulates and keeps the immune system strong and functioning for overall health.
Watch the 2 brief videos below, in which natural physician Dr. Fred Pescatore shares his insights on AHCC as the #1 best selling nutritional supplement in Japan that is used for over 700 hospitals, how it helps to support immune system without overstimulation, and how AHCC helps improve immune support against flu viruses and infections.
Best AHCC Supplement Brands Overview
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We further look into the medical study, clinical results, and AHCC supplement user reviews on how AHCC / Shiitake mushrooms help to boost their body immune support:
AHCC Immune Support Dosage Review: Clinical Study Results #1
Does AHCC have immunomodulatory and anti-cancer effects in cancer patients?
11 cancer patients with advanced malignancies were treated with AHCC for up to 17 months. Tumor-associated antigens (TAAs) for each type of malignancy was measured prior to AHCC treatment and at 3- to 40-week intervals. Natural killer (NK) cell activity was also monitored.
3 grams of AHCC per day.
Supplementation with AHCC showed positive clinical results with:
- A significant decline in TAA occurred in 8 out of the 11 patients with different types of malignancies.
- In vitro studies showed that AHCC possesses suppressive effects on tumor cell growth.
The high augmentory effect of AHCC and the absence of notable side effects make AHCC a promising immunotherapeutic agent for the treatment of cancer patients.
Shiitake Mushrooms Immune Support: Clinical Study Results #2
Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults.
52 healthy males and females, aged 21-41 years, participated in a 4-week parallel group study, consuming either 5 or 10 g of mushrooms daily. Each subject had blood drawn before and after 4 weeks of daily Shiitake mushrooms consumption.
Eating Shiitake mushrooms for 4 weeks resulted in greater ability to express activation receptors, suggesting that consuming mushrooms improved cell effector function.
Regular Shiitake mushrooms consumption resulted in improved immunity, as seen by improved cell proliferation and activation and increased sIgA production.
AHCC Immune Support Dosage Review: Research Study Results #3
Immunological effect of AHCC in healthy volunteers: a double-blind, placebo-controlled trial.
21 healthy volunteers receive placebo or AHCC for 4 weeks, and a series of indices were measured by the researchers including Natural killer (NK) cell activity, proliferative response of T lymphocytes toward mitogen, cytokine production stimulated by lipopolysaccharide, etc.
3 grams of AHCC per day.
After AHCC intake, the AHCC group with 10 volunteers had:
- significantly higher number of total DCs compared to baseline and values from control subjects.
- significantly higher number of DC1s than at baseline.
- significantly increased DC2s and Allogeneic mixed-leukocyte reaction (MLR) vs controls.
No significant differences in PHA, NK cell activity, and cytokine production were found.
AHCC intake resulted in the increased number of DCs and function of DC1s, which have a role in specific immunity.
AHCC Cancer Patient: AHCC User Forum Reviews on Immune Boost
- carolwxyz99, commented at Phoenix Rising:
‘..I have been on AHCC for about 2-3 years now – taking 2000-3000 mg a day. I developed breast cancer on top of my ME/CFS and most integrative cancer docs suggest mushrooms as cancer prevention. I am sensitive to many moulds and fungi and could not tolerate many of the mushroon products but I have been fine with AHCC. The only other mushroom I can tolerate is reishi mushroom when it is boiled with chinese herbs (I can’t tolerate reishi in powder or a tincture). I am very sensitive to products which boost the immune system as they tend to make me flu-like, and usually respond better to immune modulators. I am, however, fine with AHCC – it has not stimulated my immune system in the wrong way.‘
AHCC Immune Support Booster Supplement: User Reviews, Results, and Testimonials.
Many AHCC users testified that this Shiitake mushroom extract supplement helped to strengthen their immune system for many years with great success, by fighting off a variety of illnesses including flu, cold, tickle in throat, and many more.
Indeed, there are also pet owners who gave AHCC for dogs and cats to help cancer treatment recovery and boost the immune support.